DNA display of PNA-tagged ligands A versatile strategy to screen libraries and control geometry of multidentate ligands
نویسنده
چکیده
Over the past decade, several technologies have emerged to access nucleic acid-tagged libraries and select the fittest compound within such libraries. This perspective focuses on recent development with PNA-tagged small molecules displayed on DNA templates for screening purposes and to probe the optimal geometry in multivalent interactions. WINSSINGER, Nicolas. DNA display of PNA-tagged ligands: A versatile strategy to screen libraries and control geometry of multidentate ligands. Artificial DNA, 2012, vol. 3, no. 3, p. 1-4 DOI : 10.4161/adna.21108
منابع مشابه
A versatile strategy to screen libraries and control geometry of multidentate ligands
Over the past decade, several technologies have emerged to access nucleic acid-tagged libraries and select the fittest compound within such libraries. This perspective focuses on recent development with PNA-tagged small molecules displayed on DNA templates for screening purposes and to probe the optimal geometry in multivalent interactions. WINSSINGER, Nicolas. DNA display of PNA-tagged ligands...
متن کاملDNA display of PNA-tagged ligands
Over the past decade, several technologies have emerged to access nucleic acid-tagged libraries and select the fittest compound within such libraries. This perspective focuses on recent development with PNA-tagged small molecules displayed on DNA templates for screening purposes and to probe the optimal geometry in multivalent interactions.
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